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1. Blood brain barrier is formed by:

Capillary endothelium

Continuous basement membrane

Pericytes

All of above

None of above

2. Total power of the eye is 59 diopters. Main role is maintenance of this power as performed by:

Anterior surface of cornea

Lens

Vitreous Humor

Retina

Posterior surface of cornea

3. In patient with increased bleeding time, what could be the cause of bleeding:

Prothrombin Deficiency

Hemophilia – A

Vitamin - K deficiency

Protein - C deficiency

Von Willebrand's disease

4. What is the nerve supply of tip of nose:

Ophthalmic nerve

Maxillary nerve

Mandibular nerve

Facial nerve

Cervical plexus

5. Parasympathetic stimulation caused:

Bronchodilation

Decreased gut motiilty

Opens intestinal sphincters

Constipation

Tachycardia

6. Which of the following is the site of fusion of binocular vision:

Optic chiasma

Lateral geniculate bodies

Retina

Visual cortex

Optic nerve

7. A newborn baby with hydrocephalus has a swelling in lumbosacral spinal region, which contains neural tissue in it. What could be the probable diagnosis of this patient:

Spina bifida

Meningocele

Meningomyelocele

Meningoencephalocele

Meningohydroencephalocele

8. Which of the following is most strong antioxidant:

Glutathone

Vitamin - E

Vitamin - C

Ceruloplasmin

Catalase

9. Most early diagnosis of Vitamin-A deficiency is:

Bilot spots in cornea

Night blindness

Keratomalacia

Chielosis

Hyperkeratosis

10. A patient presents with recurrent epistaxis. Investigation reveal decreased factors II, VII, IX, X& protein-C which of the following is most likely diagnosis of this condition:

Christmas disease

Hemophillia

Vitamin-K deficiency

Von willebrands disease

Liver dysfunction

11. On H & E staining a student sees the hallow structure around the nucleus. What it could be:

Golgi apparatus

Lysosomes

Ribosomes

Endoplasmic reticulum

Mitochondria

12. Bitemproral vision loss is most commonly caused by:

Piuitary tumor

Crainiopharyngioma

Adenoma of hypothalamus

Section of optic tract

Section of optic nerve

13. A patient has finger like projection on upper lid. Hostopathological report shows epithelial cells along with fibrous element. What is most probable diagnosis:

Pappiloma

Basal cell carcinoma

Squamous cell carcinoma

Chalazion

Cellulites

14. Parotid gland supplied by:

GVA

GVE

SVE

SVA

GSA

15. Primary malignant melanoma of the choroids most commonly metastasizes to:

Liver

Lungs

Brain

Kidneys

Breast

16. A patient develops sensory loss over left side of body. After few days his behavior for pain is changed & he become angry after touching. Where could be the lesion in brain:

Right thalamus

Internal capsule

Cerebral cortex

Basal ganglia

Midbrain

17. A middle aged male has non-healing wound for long time in presence of regular dressing, random blood sugar is 130 mg/dl. What could be the cause of delayed healing in this patient:

Infection

Diabetes mellitus

High mobility

Foreign body in wound

Vascular insufficiency

18. In a patient with sympathetic stimulation, what effect will occur on his heart:

Decreased rate

Coronary vasoconstriction

Hyperpolarization of SA node

Decreased AV nodal delay

Decreased stroke volume

19. Which of the following is diagnostic of granuloma:

Giant cells

Epithliod cells

Multinucleated cells

Fibroblasts

Caseation

20. Medial orbitotomey is done in a patient with tumor in orbit. Now he is complaining of numbness at upper part of head up to vertex & medial part but medial part is intact. Which of the following nerve is damaged:

Supraorbital nerve

Supratrochlear nerve

Superior orbital nerve

Inferior orbital nerve

Fascial nerve

21. In inferior wall Myocardial Infraction, which artery should be blocked:

Left marginal artery

Diagonal artery

Right coronary artery

Right marginal artery

Posterior Interventricular artery

22. Oxygen level in the blood will decrease in:

Hypovolumic shock

Anemic Hypoxia

Hypoxic Hypoxia

Congestive Heart Failure

Acidosis

23. A male patient has antibodies against FSH RECEPTORS. Which of the following will be lower than normal in this patient:

LDL cholesterol

Hemoglobin

Sperm count

Blood Sugar

Triglycerides

24. Brucellosis is Transmitted by:

Files

Raw Fish

Unpasteurized Milk

Air Borne

Blood Transfusion

25. Week pregnant women has Irregular Uterine Contractions. Which of following drugs will be beneficial for this lady:

Progesterone

Estrogen

Prolactin

Oxytocin

26. The Diagnostic finding on investigations of Metabolic Alkalosis is:

HCO3 more then 24meq/L

CO2 more then 24meq/L

PH less than 7.4

Decreased O2 in blood

Increase serum carbonic anhydrase

27. A 6 cm Lump in the breast removed. Four Lymp nodes & skin were involved. Biopsy declared invasive Dectal Carcinoma. This tumor is called HIGH-GRADE because:

Lymph node involvement

Skin involvement

Size of tumor

Pleomorphism

Duct involvement

28. Which of the following is the characteristic of lgM:

It provides mucosal barrier

It is in highest concentration in serum

It is smallest molecule

It is largest Molecule

It crosses the placenta

29. Which of following structures in the mouth is derived from Ectoderm:

Epithelium of the tongue

Submandibular gland

Mylohyoid muscle

Epithelium of parotid gland

Tonsil

30. A young patient’s blood pressure is 150/95. his serum Rennin level is higher than normal. Which of the following is the STIMULUS for this increased level of rennin:

Essential hypertension

Increased delivery of sodium to Renal tubules

Increased sympathetic stimulation via Renal nerves

Vasodilatation of Renal arterioles

Increased blood flow to the kidneys

31. A young women, complains of Dry mouth & Dry eyes. Which investigation will give clue to her diagnosis:

ANA

Anti-ANA

RA factor

Anti - SS A/B

ANCA

32. Regarding SA Node:

Its resting membrane potential is - 65 to -85 volts

It automatically generates impulses, creating rhythmic heartbeat

Its membrane is impermeable to Na ions

It is supplied by left coronary artery

It lies in the septum

33. During the stretch in the Skeletal Muscle, which of the following changes will occur in the Nuclear Bag fiber:

They increase impulse generation

They remain static

They decrease impulse generation

They increase oscillation

They inhibit muscle contraction

34. which of the following structures is produced in 3rd week of development:

Thyroid gland

Parathyroid gland

Genital ridge

Heart tube

Tonsil

35. Antibodies are produced by:

Lymphocytes

Plasma cells

T-Cells

Neutrophils

Endothelium

36. Pulmonary Artery pressure increases in:

Exercise

Hypoxia

Anemia

Hypovolumic Shock

Hypertension

37. Defect in the formation of Bulbus Cordis resulting all of following EXCEPT:

ASD

VSD

Hypertrophy of right ventricle

Congenital cyanosis

Transposition of great vessels

38. Regarding the vibration Sense all are correct EXCEPT:

It is lost in Diabetes

Its fibers are traveling in the dorsal columns

Its receptor is Pacinian Corpuscle

Its receptor is Meissener's corpuscle

Is highly correspond to the bony portions

39. A patient with aplastic anemla is given Anti Lymphocytic Globulin (ALG). One week later he develops Skin rashes, mechanism for presentation:

Arthus reaction

Type - I Hypersensitivity

Type - II Hypersensitivity

Type - III Hypersensitivity

Type - IV Hypersensitivity

40. The most common site of Fertilization in humans is:

Ovary

Uterus

Fallopian tube

Cervix

Peritoneal cavity

41. Patients comes with deviation of tongue to right side. Decreased sense of touch and vibrations, the artery commonly involved in brain is:

PICA

AICA

Anterior Spinal

Posterior Cerebral

Superior Cerebral Artery

42. Most common site of malignancy in patients suffering from nuclear outbreak:

Haematopoietic

Thyroid

Lung

Breast

Bones

43. Least common site for ectopic pregnancy would be at:

Ovaries

Pouch of douglus

Greater omentum

Fallopian tubes

Cervix

44. Most sensitive cells to hypoxia are:

RBCs

Neurons

Nephrons

WBCs

Platelets

45. Following is not a tumor marker:

PALP

CEA

bHCG

AFP

Acid Phospatase

46. Tyrosine derivative does not include:

TSH

Adrenaline

Nor adrnaline

Prolactin

Dopamine

47. Organ having least chances of infarction:

Lungs

Heart

Kidneys

Liver

Spleen

48. Least chances of renal stones is associated with:

Hyperlipidemia

Hyper PTH

Hyper vit.D

Infections

Hyperurecemia

49. Patient with injury to left 8th cervical segment of spinal cord will not show following sign:

Decreased sense of position

Vibration below lesion on same side

Extensor plantar on left side

Dec power of muscles below the lesion on same side

Dec sense of pain and temperature belowthe lesion on same side

50. Patient with bone pains having normal Ca, inc Alkaline phosphatase. Most likely suffering from:

Pagets disease

Hyper PTH

Hyper Vit D

Bone mets

Osteomalacia

51. Bile salts are reabsorbed from the:

Duodenum

Jejunum

Ileum

Colon

Rectum

52. In Turner syndrome, the genotype would be:

XXY

XYY

53. Presence of pancreatic tissue in gastric mucosa is termed as:

Hamartoma

Metaplasia

Neoplasia

Choriostoma

Dysplasia

54. Patient with old history of adenocarcinoma of colon operated for polypectomy, on histologic evaluation pathologist labeled it as benign growth with no chances into malignant transformation, it would be:

FAP

Villous adenoma

Tubular adenoma

Tubulovillous

Metaplastic polyp

55. Man in suffering from testicular Carcinoma, the lympahtic drainage of testicle is into:

Para aortic Lymph nodes

Pre aortic

Superficial inguinal

Internal iliac

External iliac Lymph nodes

56. Mesothelioma is associated with:

Vinyl chloride

Silica

Asbestos

Copper dust

Carbon

57. Foetal period starts after which week:

11th

8th

12th

16th

21st

58. Soldier comes with heavy bleeding. The ideal fluid replacement would be:

Packed RBCs

Crystallines

Colloids

Whole blood for 3 days

Whole blood for 18 days

59. Vertebrae is derived from:

Myotome

Sclerotome

Dermatome

Ectoderm

Endoderm

60. Largest total cross-sectional and surface area is of:

Artery

Arterioles

Capillaries

Venules

Veins

61. Esophagus histology:

Covered by squamous ep

Has str. sq in upper 1/3

Has 3 layers of muscles

Esophageal opening acting as anatomicalsphincter

62. Structures entering thoracic inlet:

Accessory nerve

Aorta

Superior vena cava

Azygous Vein

Left recurrent laryngeal nerve

63. Example of carrier mediated counter transport:

Na - glucose transport

Active transport

Passive transport

H transport

Diffusion

64. Alpha recptors effects:

Inc HR

Lipogenesis

Midriasis

Piloerector contraction

Bronchodilator

65. Hypoglycemia increases:

SSK

Somatostatin

Gastrin

VIP

Secretin

66. Cushing’s triad:

Inc ICP, HTN, Bradycardia

Inc ICP, hypoTN, Bradycardia

Inc ICP, hypoTN, Tachycardia

Inc ICP, HTN, Tachycardia

Dec ICP, HTN, Tachycardia

67. Somatostatin dec sec of which hormone:

ADH

Insulin

Oxytocin

Prolactin

Thyroid hormone

68. Digoxin toxicity:

Inc K

Inc Mg

Dec Ca

Dec Na

Alkalosis

69. Following is true regarding sterilization:

Repeated heating denatures polyvencyl tubings

Autoclaving is heating objects at 121 degC at 15 psi for 3min

Radiation (UV light)

Dry heat

Formaldehyde

70. Pt complains of chest pain for more than 30 min. ECG shows changes in V1-V4. It denotes:

Anterior wall MI

Anterolateral MI

Inferior wall MI

Lateral wall MI

Inferior wall MI

71. Depolarization of cell is maintained by:

Na influx

Ca efflux

Ca influx

K influx

Na efflux

72. Spinal cord ends at the level of lower border of:

L2 vertebra

L3 vertebra

L4 vertebra

L5 vertebra

S1 vertebra

73. Regarding Hyperoxia. All true except:

Retrolental fibroplasia

Atelectasis

Dec surfactant prod

CV depression

Anemia

74. Pacinian corpuscles related to:

Touch

Vibration

Pressure

Rapidly adapting pain

Slowly adapting pain

75. Drug that inc extracellular K (moves K out of the cell):

Angiotensin

H2CO3

Carbonic anhydrase

Exercise

76. Thirst is decreased by:

ADH

Aldosterone

Ag II

Baroreceptor efferent

Inc Hematocrit

77. Muscle of quiet inspiration:

Diaphragm

Rectus abdominis

Internal intercostals

innermost intercostals

External intercostals

78. Dry mouth increases all except:

Thrist

ADH

Ag II

Plasma osmolarity

Plasma volume

79. Gastric acid is stimulated by:

Gastrin

CCK

Secterin

GIP

VIP

80. Which of the following fungi produce life threatening infection in patients with diabetics ketoacidosis:

Candida Albicans

Histoplasmosis

Mucor

Aspergillus

Blastomycosis

81. A patient has non-reactive HBs Ag, non reactiveHBe Ag & reactive anti HBc Ab. This stages of patient indication what:

Acute infection

Carrier

Transient resolving stage of hepatitis

Immunized

Chronic active disease

82. A Patient has enlaged parotid gland with pain in this region. Which nerve is carrying pain fibers from the parotid gland:

Auricuolotemporal nerve

Glossopharyngeal nerve

Facial Nerve

Temporal nerve

Greater auricular nurve

83. A Patient has anemia, hyper-segmented Neutrophils on peripheral blood examination & neurological manifestations. Which type of anemia he is suffering from:

Folic acid deficiency anemia

Iron deficiency anemia

Pernicious anemia

Thalasemia

Autoimmune hemolytic anemia

84. A young child has increased BP in upper limbs while decreased BP in lower limbs. Pulse in also week. What is the probable diagnosis:

Preductal coarctation of aorta

C..S.D

Patent ductus arteriosus

Postductal coarctation of aorta

Transposition of great vessels

85. In case of typhoid fever of 06 days. Which investigation is of first choice:

Widal test

Blood culture

Typhi dot test

Bone marrow culture

Urine culture

86. In a patient with diabetes, which is the best antihypertensive drug:

Captopril

Diuretic

Varapamil

Propranolol

Diltiazim

87. Urine Examination of a patient with diabetes demonstrates. Ketone-bodies. What is the mechanism of formation of these ketone-bodies:

Insulin deficiency

Hyperglycemia

Defective fat metabolism

Hypoalbubinemia

Defective glucose metabolism

88. After giving blood transfusion, a patient develops hypersensitivity reaction. Which type of hypersensitivity reaction is this:

Type I Hypersensitivity

Type II Hypersensitivity

Type III Hypersensitivity

Type IV Hypersensitivity

A.D.C.C

89. A Patient develps lesion in the Caudate nucleus. Which is most common clinical feature Indicating this lesion:

Chorea

Intentional Tremor

Resting Tremor

Hemiplagia

Nystygmus

90. Heme Binds with:

Albumin

Globulin

Hemopexin

Heptoglobin

Macroglobulin

91. Best pulmonary function test for the asthma is:

FEV - 1

Residual volume

Tidal volume

Vital capacity

Inspiratory capacity

92. A pregnant lady develops pain few hours after delivery. E.C.G. shows S1, Q3 and T3. What is another investigation most appropriate for the diagnosis of this case:

X-Ray

Gallium Scan

CPK

Ultrasound

93. In a patient diarrhea are corrected after the fasting. Which is most likely type of diarrhea:

Infectious

Psychogenic

Osmotic

Metabolic

Toxic

94. A diabetic Patient is advised fasting blood glucose level. At what value doctor is confusing & needs further evaluation with glucose tolerance test:

04 m mol / L

05 m mol / L

07 m mol / L

10 m mol / L

15 m mol / L

95. A patient has Aphasia & Facial nerve palsy on same side. Which artery is most likely blocked:

Anterior cerebral artery

Posterior cerebral artery

Middle cerebral artery

Anterior division of middle cerebral artery

Posterior division of middle cerebral artery

96. A young female is having Goiter. She feels difficulty in breathing while lying down. Which type of the goiter she is having:

Retrosternal goiter

Malignant goiter

Toxic goiter

Diffuse goiter

Simple goiter

97. Regarding L & D sugars:

D sugar has - OH on right

L sugar has - OH on right

D sugar has - OH on left

D sugar has no - OH

L sugar has no – OH

98. Councilman bodies are formed in the process of:

Infection

Apoptosis

Trauma

Necrosis

Atrophy

99. A middle aged male presents with joint pain since one week. His serum Uric Acid level is 156 mg/dl. What is the best investigation for confirmation of the diseases:

R.F

Synovial fluid for polarized light

Synovial fluid for Culture & Sensitivity

X-Ray of joint

E.S.R

100. A patient comes to you in ill condition. His blood pH is 7.3 PCO2 is 44 mmHg & HCO3 is 17 meq/L. What diagnosis you are thinking of this patient:

Metabolic alkalosis

Metabolic acidosis

Respiratory acidosis

Compensatory acidosis

Compensatory alkalosis

Time is Up!

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CPSP Exam Demo Questions
FCPS Part 1 Questions with CPSP Keys
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8 COMMENTS

dr.reenalakhmiani@gmail.com September 8, 2020 At 8:23 pm

Plz arrange another test also from past pprs this ppr help us

- admin September 8, 2020 At 8:27 pm
  
  You mean Mock Tests?
  
Farheen Fatima September 12, 2020 At 7:26 am

Thank you:)

- admin September 12, 2020 At 2:22 pm
  
  Please share with your friends.
  
bazgha muneer October 16, 2020 At 9:43 am

It’s good effort

- admin October 30, 2020 At 11:32 am
  
  Thanks alot.
  
Shabirhasan January 31, 2021 At 11:35 am

Well done

- admin January 31, 2021 At 12:20 pm
  
  Thanks for appreciation, kindly share with your friends so that they can have real exam experience.

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